Caitlin Foord scored two goals to help Arsenal finish first in their UWCL group and Sam Kerr found the back of the net at Stamford Bridge for Chelsea, while Lyon booked the last quarter-final spot.
Read our wrap of all the action and watch the highlights in the player above!
Group A
Sam Kerr's Chelsea ensured a first-place finish in the group after beating Lydia Williams' Paris Saint-Germain 2-0 at Stamford Bridge.
A tight first-half tussle saw the Blues go into the break one goal up, with Kerr picking the ball up just outside the box and finishing in the top corner past Sarah Bouhaddi.
Chelsea started the second-half right where they left off, with the home side pouncing on a poor ball off from the back and Kerr turning provider for Lauren James.
James added a third after the hour-mark, making the task of PSG beating them by two goals to leapfrog them unreachable as the Blues won 3-0 to PSG.
Group C
Steph Catley and Caitlin Foord's Arsenal finished first in their group with a dominant 9-1 win over Zürich, with Foord finding the back of the net twice and bagging two assists in the win.
Frida Maanum opened the scoring with a superb free-kick before Foord doubled the advantage soon after. Foord then set up Mannum for her second at the half-hour mark and Stina Blackstenius made it four just before the break.
The second half started in a similar fashion with Maanum completing her hat trick, and then Blackstenius made it 6-0. Zürich clawed a goal back from the spot, with Foord then restoring the six-goal advantage after picking up a poor back pass from the Zürich defence.
Catley played her part in one goal, winning a penalty kick after making a bursting run into the box and sending a cross in that met the hand of a Zürich defender. Captain Kim Little stepped up to slot the penalty.
Foord set up Mana Iwabuchi for the Gunners' ninth of the evening, ensuring they finished the group in 1st place.
In other group action, Ellie Carpenter's reigning UWCL champions, Lyon, booked the last spot in the quarter-finals with a narrow 0-0 win against Juventus.
Going into the final matchday Lyon knew they would go through if they avoided defeat against Juventus. A string of saves from former Lyon goalkeeper Pauline Peyraud-Magnin kept the reigning champions at bay denying Eugénie Le Sommer and Delphine Cascarino from opening the scoring.
Lyon qualifies second in the group behind Arsenal and will face the first-place team from the other groups in the quarter-finals.
Group D
Lastly, Teagan Micah's FC Rosengård went down 6-0 to Barcelona at Camp Nou, going down fighting to the Spanish giants in their last UWCL game of the season.
Rosengård went into the final matchday of the group stage unable to progress to the next round, with Micah not appearing in the fixture.
Three goals in either half to Barca helped the former champions qualify first in the group.